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CSC8309 -- Gene Expression and Proteomics

Introduction

This module provides an introduction to gene expression and proteomics. In particular, as you might expect, we will focus on the bioinformatics analyses rather than the experimental side, although we will talk about experimental design.

Gene Expression and Proteomics

This years module will be taught by Phillip Lord (PL), Simon Cockell (SJC) and Dan Swan (DS) of the Bioinformatics Support Unit, with a guest lecture from Jochen Weile.

Assessment

This module is assessed entirely through coursework. The deadline for both assessments will be the last day of the 3 week module. The assessment will consist of two pieces of work, one relating to the microarray practical, one relating to the proteomics practical.

Both assessments will take the form of a 4 page report. As normal, this should be submitted according to the author guidelines for Bioinformatics. The page limit is strict, and is not a reflection on the amount of effort that should be put into the work.

Lectures

Mon 21/02 14-16 Introduction, PL
Wed 23/02 14-15 Experimental Design, SJC
Wed 23/02 15-16 Gene Expression Technology, PL
Fri 25/02 14-15 Sources of Variability, PL
Mon 28/02 14-16 Proteomics SJC
Tue 01/02 09-13* Proteomics Practical SJC
Wed 02/03 14-16 Paper Analysis/Data Standards PL
Mon 07/03 14-16 Case Studies (JW, SJC)
Tue 08/03 09-13* Microarray Practical PL, DS
Wed 09/03 12-16 Support Session
Fri 11/03 13-17 Support Session

For both practical sessions, support will be from the start of the day (9am), and you should arrive at this time. For the proteomics practical, Simon will be present in the morning, and we expect that you will be able to finish the practical in this time. For the microarray practical, Dan and I will be present from 9am to 1pm.

Most people should be able to complete within this time, but we do not guarentee this. The work of the practical may take longer, and you should schedule for the entire day.

Lecture notes

Any Lecture Notes will appear here.


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