Charles Winterhalter

photo

Centre for Bacterial Cell Biology
School of Computing Science
Newcastle University

Room: 922
Tel: +44 (0)7941 051 761
E-mail: c.winterhalter@newcastle.ac.uk

PhD student
Research engineer at the Institute of Systems and Synthetic Biology, France
M.Sc. in Systems and Synthetic Biology at Université d'Évry Val-d'Essonne, France
Master I in Bioengineering and Computer Science (Bioinformatics) at Université d'Évry Val-d'Essonne, France
B.Sc. in Bioengineering and Computer Science (Bioinformatics) at Université d'Évry Val-d'Essonne, France
Research Interests
bioinformatics, synthetic and systems biology, modelling
Supervisor
Prof. Natalio Krasnogor

Research

Genome is the secret of life, and that's why I initially started studying bio-engineering. Besides, as there is no smoke without fire, there is no biology without informatics. I therefore chose to go through bioinformatics during my B.Sc. at the University of Evry Val-d'Essonne.

I carried out my B.Sc. project at the Institute of Systems and Synthetic Biology (iSSB) in France where I participated to the engineering of genetic oscillators as well as visualising conjugation events in microfluidics biochips. Later on, I spent a few other months at iSSB as part of my Master I in which I developed a pipeline for predicting enzymatic activities.

Then I completed my studies by a M.Sc. in Systems and Synthetic Biology during which I went to the University of Nottingham and had the opportunity to meet Prof. Natalio Krasnogor, who now is my PhD supervisor at Newcastle University. We developed together, with the worth contribution of Dr. Paweł Widera, a Cytoscape plugin called JEPETTO that performs integrated gene sets analysis using enrichment and topological features.

I further developed another Cytoscape app back at iSSB called PEPPER, which expands protein complexes derived from pull-down assays such as single AP/MS experiments and finds meaningful pathways / processes.

Finally I started my PhD in March, 2014 with Natalio and now focus on the de novo engineering of biological parts and their computational characterisation.